Charlie Thorne's 12, bored in college, and using only 1/4 of her immense brain when her half-brother CIA agent pulls her off the ski-slopes of Colorado to save the world from a badly-organized group of anti-immigrant, racist louts from Germany calling themselves the "Furies."
They want to find Einstein's last equation, known as Pandora (which can blow us up or bring us hope, depending on who gets it first), and purge the world of POC.
Of course, there's a supposedly-dead CIA-agent double-cross in there, too, who turns out to be the real bad guy, and even though Charlie has only taken basic martial-arts classes, she manages to avoid any real harm or foul, while inflicting significant damage on the bad guys and the Mossad.
There's no real plot twist, just a fast paced-race to the end and a super-duper smart, disaffected Charlie who has a change of heart by the end -- sorta. It's set up nicely for the next book.